Toxicology and industrial health

01 18 October 2026

DOI 10.1177/07482337261500552

Prenatal microplastic exposure-induced testicular developmental toxicity and its long-term hazards in male rat offspring

Open DOI

Linguo Pei, Yuanyuan Zhang, Wenjuan Zhang et al.

The pervasive environmental presence of microplastics (MPs) raises concerns regarding their potential impacts on reproductive health, particularly in the context of prenatal exposure. This study aimed to establish a polystyrene microplas...

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02 16 September 2026

DOI 10.1177/07482337261486650

Silica-induced CDK/CDKI dysregulation in alveolar macrophages and its implications in pulmonary fibrosis via altering macrophage fate: A review

Open DOI

Yan-Rui Liu, Yuan-Yuan Fu, Hui-Jie Hu et al.

Cyclin-dependent kinases (CDKs) and cyclin-dependent kinase inhibitors (CDKIs) are a pair of antagonistic regulators of cell-cycle progression. Both exhibit aberrant expression in silica-exposed alveolar macrophages (AMs), thereby alteri...

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03 11 September 2026

DOI 10.1177/07482337261486662

Protective effects of hesperidin against nano-alumina in the rat brain: Bioaccumulation, oxidative stress, and inflammatory biomarkers

Open DOI

Dina M. El-Gridly, Ahmed R. Ezzat, Haitham S. Mohammed et al.

The protective efficiency of hesperidin (Hesp) against the bioaccumulation and neurotoxicity induced by nano-alumina (Al 2 O 3 NPs) in three brain regions (BR), hippocampus (Hippo), cortex (Cor), and brainstem (BS), has been investigated...

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04 9 September 2026

DOI 10.1177/07482337261486628

Resveratrol inhibits coal dust nanoparticle-induced acute lung epithelial cell injury and chronic pulmonary fibrosis

Open DOI

Amin Li, Ge Zhou, Ruikai Wang

Coal dust nanoparticles (CD-NPs) are a major risk factor for pneumoconiosis. We evaluated the protective effect of resveratrol against pulmonary fibrosis induced by CD-NPs in pneumoconiosis. Our results showed that CD-NPs exposure signif...

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05 9 August 2026

DOI 10.1177/07482337261472599

Impact of pesticides lambda-cyhalothrin, emamectin benzoate, and thiophanate-methyl used alone and in mixtures on reproduction and oxidative stress markers in male Wistar rats

Open DOI

Narimene Chelbi, Leila Mallem, Hanene Chaabane et al.

Pesticide exposure is a growing public health concern, particularly in agricultural regions where workers and communities encounter multiple chemical compounds simultaneously. Although previous studies have investigated the reproductive ...

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06 31 July 2026

DOI 10.1177/07482337261467527

Effects of sub-acute aluminium phosphide exposure on hepatorenal biomarkers and antioxidant defense in rats

Open DOI

Ibtissem Anguel, Leila Kirane-Amrani, Tahar Tata et al.

Aluminium phosphide (AlP) is a well-known toxic pesticide, but its dose-dependent toxicity and the distinction between safe and harmful exposure levels remain poorly established. Thus, the present study aimed to investigate the dose-depe...

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07 31 July 2026

DOI 10.1177/07482337261472039

Hematological changes in formaldehyde-exposed workers: A critical review and meta-analysis

Open DOI

Reza Pourbabaki, Fatemeh Rahimian, Mohammad Ebrahim Ghaffari et al.

Formaldehyde (FA) is a widely used chemical with known carcinogenic properties, particularly for the upper respiratory tract. Concerns about probable FA-induced hematotoxicity and leukemia have sparked investigations into its health risk...

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08 29 July 2026

DOI 10.1177/07482337261471257

Toxicological implications and human health risk assessment of heavy metal contaminated green leafy vegetables and their cultivated soil

Open DOI

Varun Shankarappa, Prabhurajeshwar Chidre, Ajay Kumar Oli et al.

In the present study, fourteen green leafy vegetables, including spinach, coriander, spring onion, curry, dill, fenugreek, green amaranth, and red amaranth, along with their rhizospheric soils from Chitradurga, Davangere, Tumkur, and Hav...

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09 24 July 2026

DOI 10.1177/07482337261469287

Molecular mechanisms of heavy metal-induced cancer: Insights from animal models and human implications

Open DOI

Sneha Dhanasekaran, Kottila Veettil Dhaneesh

Heavy metals and metalloids, including arsenic (As), cadmium (Cd), chromium (Cr), nickel (Ni), lead (Pb), and mercury (Hg), are well-recognised human carcinogens, and the molecular mechanisms underlying their carcinogenicity are incomple...

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10 21 July 2026

DOI 10.1177/07482337261467897

The effects of flurochloridone exposure during pregnancy on maternal and fetal development

Open DOI

Rui Li, Su Zhou, Hongyan Zhu et al.

Flurochloridone (FLC) was classified as “May cause harm to the unborn child” by the European Food Safety Authority (EFSA). Because of the potential for occupational exposure to FLC, and the lack of reported maternal and fetal data, we in...

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