The primary care companion for CNS disorders

01 15 October 2026

DOI 10.4088/pcc.26cr04300

Acute Psychosis and Delirium During Menstruation in a Premenopausal Woman With Urinary Tract Infection

Open DOI

Sara Ellias, Aateqa Hashmi, Jisselly Sanchez Salcedo et al.

The authors report a case of recurrent delirium and psychosis temporally associated with co-occurring urinary tract infection and menstruation in a premenopausal woman.

02 15 October 2026

DOI 10.4088/pcc.26cr04274

Vintage Find, Modern Emergency

Open DOI

Patrick L. Tomlinson, Nasuh Malas

The authors report a case of an adolescent who ingested what he believed to be an over-the-counter cold preparation obtained at an estate sale with the intent to “get a high.”

03 13 October 2026

DOI 10.4088/pcc.26cr04240

Forty Years of Untreated Anorexia Nervosa

Open DOI

Joana Romão, Marta Rebelo, Patrícia Baronet et al.

The authors present the case of a patient with a nontreated anorexia nervosa for more than 40 years, who developed severe medical complications secondary to the untreated psychiatric illness.

04 13 October 2026

DOI 10.4088/pcc.26cr04238

Use of Electroconvulsive Therapy and Ketamine in a POLG-Related Disorder

Open DOI

Joana Romão, Marta Rebelo, Patrícia Baronet et al.

Ketamine therapy and ECT are 2 treatment modalities that may be considered in patients with a POLG-related disorder and mood symptoms.

05 8 October 2026

DOI 10.4088/pcc.26nr04252

Skin and Brain in Bipolar Disorder

Open DOI

Drew Mack, Nina Modanlo, Ingyun Park et al.

This narrative review synthesizes dermatologic adverse effects associated with commonly used psychiatric medications and psychiatric adverse effects associated with systemic dermatologic therapies in patients with bipolar disorder

06 8 October 2026

DOI 10.4088/pcc.26cr04277

Limb Loss After Intentional Dry Ice Frostbite in a Patient With Body Integrity Dysphoria and the Role of Online Identity Communities

Open DOI

Ann C. Schwartz, Gregg A. Robbins-Welty, Caroline Stiles et al.

A transgender young adult was admitted to the hospital after intentionally submerging both feet in dry ice, resulting in severe frostbite and requiring bilateral below-knee amputations.

07 6 October 2026

DOI 10.4088/pcc.26f04249

Managing the Sequelae of Delirium Associated With Critical Illness

Open DOI

Joseph D. Dragonetti, Maureen K. Cassady, Emma R. Torncello et al.

While symptoms of delirium have traditionally been considered transient and fully reversible, many patients have symptoms for months to years, while some fail to return to their baseline.

08 6 October 2026

DOI 10.4088/pcc.26cr04223

Early Palliative Care and Structured Serious Illness Communication in a Refugee Patient With Amyotrophic Lateral Sclerosis

Open DOI

Jillian Rankin, Carina Oltmann, Emily Pinto Taylor et al.

This case illustrates how early collaboration with an inpatient palliative care interdisciplinary team can promote patient-centered, goal-concordant care in the acute hospital setting.

09 1 October 2026

DOI 10.4088/pcc.26cr04260

Artificial Intelligence–Associated Psychosis

Open DOI

Jamie Harbourd, Suresh Yadav, Kagan Temur et al.

The authors present the case of a 27-year-old woman with psychosis, in whom the use of generative AI colored her clinical presentation.

10 1 October 2026

DOI 10.4088/pcc.26cr04227

When the Therapist’s Thoughts Change, the Patient Changes

Open DOI

Takuji Inagaki

The author describes a perplexing case of a 14-year-old girl with autism and the use of a psychotherapeutic treatment intervention based on a Buddhist concept.