Impact Factor
4.57
Journal Citation Impact
Estimated influence, citation density, publishing volume, and citation integrity from the analytics table.
Citation rate
6.51
7,911 total citations
h5-index
93
h5 depth signal
Cited share
90.0%
1,307 of 1,452
Total citations
7,911
Citation footprint
Metric signal
5.66
External metric anchor
Self-citation
3.2%
255 self-citations
Citations Trend
Monthly Publications Cadence
Citing Geographic Demographics
United States
3,784
United Kingdom
1,319
Germany
977
China
714
France
645
Citing Fields of Research
Genetics & Genomics
2,046
Neurosciences
1,673
Cell Biology
1,113
AI & Machine Learning
1,040
Protein Structure & Folding
495
Publishing Activity & Reach
Volume, recency, access pattern, and citing-community signals from the journal analytics record.
All-time article footprint
13,070
Articles tracked across the journal lifetime
Indexed publication set
1,452
1,307 cited publications
Last 12 months
1,010
84.2 publications/month
Open access share
100.0%
1,010 OA publications in the last year
Leading citing country
United States
3,784 citing publications
Leading citing field
Genetics & Genomics
2,046 citing publications
Latest tracked publication
16 October 2026
10 recent records available
Coverage & Indexing History
v1n1, June 2005-
v1n1, June 2005-
Active Coverage
Research Focus & Classification
Indexed Subjects
Neurosciences
Genetics & Genomics
AI & Machine Learning
Cell Biology
Protein Structure & Folding
Issuing & Sponsoring Bodies
Contributor
Public Library of Science
Contributor
International Society for Computational Biology
Broad Categories
Computational Biology
Neurosciences
Genetics & Genomics
Virology
Protein Structure & Folding
Tropical Diseases
MeSH Descriptors
Computational Biology
Latest Publications
Recent article records with DOI-first linking and condensed abstracts.
01
DOI 10.1371/journal.pcbi.1014028
Open DOI
Weak dispersal and landscape size inevitably promote local biodiversity in heterogeneous metacommunities of competing species
We provide a general theoretical explanation for a longstanding result in spatial ecology: weak dispersal among habitat patches promotes local species richness. Using analytical approximations of spatial Lotka–Volterra competition models...
02
DOI 10.1371/journal.pcbi.1014862
Open DOI
Computational deconvolution of drug sensitivity via single-cell–to–bulk transcriptome mapping
Analyses routinely conducted in both fundamental research and biomedical studies often report aggregate signals derived from heterogeneous mixtures of cells. These mixtures reflect the intrinsic anatomical and functional complexity of th...
03
DOI 10.1371/journal.pcbi.1014841
Open DOI
Ten simple rules for developing a reporting appraisal tool
In an ideal world, authors would report clearly and transparently exactly what they conducted. In reality, reporting is often incomplete, and key elements of research conduct are frequently missing from manuscripts. Reporting guidelines ...
04
DOI 10.1371/journal.pcbi.1014755
Open DOI
Computation-through-Dynamics Toolkit: Simulated datasets and quality metrics for dynamical models of neural activity
A primary goal of systems neuroscience is to discover how ensembles of neurons transform inputs into goal-directed behavior, a process known as neural computation. A powerful framework for understanding neural computation uses neural dyn...
05
DOI 10.1371/journal.pcbi.1014857
Open DOI
Leveraging spatial structure to design spatially-targeted malaria interventions at the community-scale
Progress in malaria control has stagnated since the early 21st century in many countries, requiring new approaches such as the use of spatially-targeted interventions. However, evidence on the effectiveness of spatially-targeted interven...
06
DOI 10.1371/journal.pcbi.1014865
Open DOI
From prompts to genomes: A constraint-first framework for AI-driven sequence design across life and viruses
A constraint-first framework for future ‘prompt-to-genome’ AI across Bacteria, Archaea, Eukaryota, and viruses is proposed. Genome-scale models can now generate long DNA sequences, and experimentally viable genome-scale designs have begu...
07
DOI 10.1371/journal.pcbi.1014863
Open DOI
Ten simple rules to build genomics capacity for routine laboratory practice in the Global South
Developing sustainable genomics capacity in the Global South requires more than technology transfer; it depends on human-centered approaches based on the workflows and existing expertise of laboratory personnel, institutional collaborati...
08
DOI 10.1371/journal.pcbi.1014393
Open DOI
MEGH-DDI: MolT5-driven edge-aware graph learning with Hop2Token representation for drug–drug interaction prediction
Drug-drug interactions (DDIs) are critical in pharmacology, as synergistic or antagonistic effects between co-administered drugs can enhance therapeutic outcomes or cause toxicity, posing major challenges for drug safety assessment and n...
09
DOI 10.1371/journal.pcbi.1014859
Open DOI
How compartmentalization and proliferation shape the splenic T cell repertoire during an immune response to a complex antigen in mice
The adaptive immune system recognizes billions of unique antigens using highly variable T cell receptors (TCRs). To what extent TCR features shape the spatial distribution of the TCR repertoire (TCR-R) within lymphoid organs remains uncl...
10
DOI 10.1371/journal.pcbi.1014869
Open DOI
Interpretable neural networks prioritize cancer driver genes from genome-wide dependency landscapes
Identifying cancer driver genes and their therapeutic impact remains a core challenge in computational cancer biology. We introduce xNNDriver and xAEDriver, two interpretable neural network frameworks that connect cancer mutations with g...
Bibliographical & Catalog Notes
Print issues ceased with v.4, no.1 (2008).
Issues 1-7, 10, 12 (2006) and Issues 7-12 (2005) never published in print.
Also issued online.
Published in association with International Society for Computational Biology.