Journal of Zhejiang University. Science. B

01 17 October 2026

DOI 10.1631/jzus.b2500391

Surficial amidogen 3D-printed poly-ether-ether-ketone (PEEK) implant promotes incision healing after chest wall reconstruction: a technical note

Open DOI

Xiao Liang, Weiwei Wu, Gandong Zhou et al.

02 12 October 2026

DOI 10.1631/jzus.b2500269

Single-cell profiling of the liver in offspring with intrauterine hyperglycemia reveals acute-phase response deficiency

Open DOI

Jiahang Mo, Jing Yan, Yi Cheng et al.

03 6 October 2026

DOI 10.1631/jzus.b2500442

CircMED17 regulates bovine adipogenesis and fat deposition via mediating the proliferation and differentiation of bovine adipocytes

Open DOI

Yuta Yang, Shaoli Zhang, Lei Chen et al.

Fat deposition is a key factor influencing beef quality. Therefore, understanding the regulatory mechanisms of adipogenesis is crucial for improving meat p

04 5 October 2026

DOI 10.1631/jzus.b2500083

Hypoxia promotes ovarian cancer progression via lnc-DARS-AS1/miR-378a-5p/SLC2A12 axis

Open DOI

Wenjie Zeng, Hubin Xu, Huafeng Shou et al.

This study aimed to examine hypoxia-induced phenotypic alterations in ovarian cancer and to elucidate the molecular mechanisms mediated by long non-coding

05 1 October 2026

DOI 10.1631/jzus.b2500788

Structural basis of calcium-sensing receptor activation by extracellular modulators

Open DOI

Xueli Zeng, Hongnan Liu, Xizhe Wang et al.

The calcium-sensing receptor (CaSR) plays a central role in maintaining systemic calcium homeostasis. In the treatment of secondary hyperparathyroidism (SH

06 23 September 2026

DOI 10.1631/jzus.b2500462

SWCNTs/PEDOT:PSS-modified microelectrode arrays reveal striatal–hippocampal neural encoding of movement initiation and place fields during goal-directed navigation

Open DOI

Jin Shan, Wei Xu, Jinping Luo et al.

Goal-directed navigation necessitates coordinated interactions among multiple brain regions, with the hippocampus and striatum playing critical roles in sp

07 22 September 2026

DOI 10.1631/jzus.b2600423

Unexpected endoscope surface phenomena in soaking mode of automated endoscope reprocessor: fluorescent tracer redeposition and persistent surface-tension bubbles

Open DOI

Mei Li, Chenying Zhou, Ting Teng et al.

摘要 随着内镜诊疗应用的日益普及, 内镜相关病原体传播风险备受关注, 但不同运行模式的全自动内镜清洗消毒机 (AER) 对内镜外表面清洗消毒效果的影响仍缺乏系统比较。 本研究对比了 AER 的三种运行模式——浸泡、 喷淋及喷淋–浸泡联合模式, 并观察到浸泡模式...

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08 22 September 2026

DOI 10.1631/jzus.b2500179

Roles of macrophages in tumor immunotherapy: metabolism, immune checkpoints, and combination strategies

Open DOI

Shan Wang, Yage Fu, Yamei Huang

Macrophages influence anti-tumor immunity through tractable metabolic and checkpoint programs. Within hypoxic, nutrient-competitive tumor beds, tumor-assoc

09 22 September 2026

DOI 10.1631/jzus.b2500424

Integrative graph deep learning with directional decoding for robust gene regulatory network inference from single-cell transcriptomics

Open DOI

Binhua Tang, Yingying Feng, Xinyu Gao et al.

While gene regulatory networks (GRNs) are fundamental to understanding complex cellular mechanisms, the accurate inference from single-cell RNA-sequencing

10 19 September 2026

DOI 10.1631/jzus.b2500181

Applications and advances of bile-based omics technologies in the diagnosis of cholangiocarcinoma

Open DOI

Taifeng Zhu, Jiali Xing, Ziyue Huang et al.

Cholangiocarcinoma (CCA) is challenging to diagnose due to its subtle symptoms and the limited sensitivity and specificity of conventional diagnostic modal