Journal of the American Association for Laboratory Animal Science : JAALAS

01 1 July 2026

DOI 10.30802/aalas-jaalas-26-034

A Practical, Noninvasive Urine Collection Method for Mice for Large Cohort Preclinical Studies

Open DOI

Neslihan Sarigul, Avery Antes, John Lukens et al.

Accurate urine collection is essential for preclinical studies involving metabolism, toxicology, and disease modeling. However, conventional methods such as metabolic caging and manual restraint are often invasive, labor intensive, prone...

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02 1 July 2026

DOI 10.30802/aalas-jaalas-26-041

Standardization of Dental Radiographic Techniques Using a Handheld X-Ray System in Rhesus Macaques (Macaca mulatta)

Open DOI

William R Fugina, Alyssa H Balzer, Victoria R Albanese et al.

Dental radiology is a valuable diagnostic tool commonly used during comprehensive oral health assessments and treatments (COHAT) and oromaxillofacial surgical procedures in companion animals and humans. However, standardized techniques f...

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03 1 July 2026

DOI 10.30802/aalas-jaalas-26-027

Robust Scoring System to Evaluate Animal Well-Being in Murine (Mus musculus) Orthotopic Breast Cancer and Ovarian Cancer Models

Open DOI

Ranya Al-Khaledy, Makiko Watanabe, Rebecca Shukla et al.

Orthotopic tumor models are critical to the development of new cancer therapies, as they have the greatest potential to mimic human cancer progression. However, such models are often underutilized due to practical challenges. These chall...

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04 1 July 2026

DOI 10.30802/aalas-jaalas-26-049

The Use of Dexmedetomidine Hydrochloride as a Single Pharmaceutical and in Combination with Ketamine for Sedation of Cynomolgus Macaques (Macaca fascicularis)

Open DOI

Wendy L Evans, Stephen W Brookshire, Jennifer R Makar et al.

Sedation in nonhuman primates (NHPs) is commonly achieved with ketamine (KET), which provides short-term (less than 30 minutes) sedation but is associated with undesirable side effects such as twitching, increased jaw tone, and hypersali...

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05 1 July 2026

DOI 10.30802/aalas-jaalas-26-039

From Mice to Moths: Practical Reasons for Considering Animal Welfare in Research

Open DOI

Jessica Cait, Aileen MacLellan, Sarah J J Adcock et al.

Considering animal welfare in research is an important part of ethical professional practice. However, not all animal species are covered by welfare legislation, resulting in less consideration for currently unprotected groups. While eth...

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06 1 July 2026

DOI 10.30802/aalas-jaalas-26-075

Implementation and Evaluation of Environment-Derived Dust-Based Environmental Health Monitoring in an Open-Top Housing Laboratory Animal Facility

Open DOI

Naoyuki Saito, Takayoshi Nakagawa, Tetsuya Fukunaga et al.

Environmental health monitoring (EHM) has gained attention as a sensitive, animal-free alternative to soiled bedding sentinel (SBS) programs for microbiologic surveillance in laboratory animal facilities. Although several EHM approaches ...

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07 1 July 2026

DOI 10.30802/aalas-jaalas-26-112

Response to the Veterinary Consortium for Research Animal Care and Welfare: Partnership Is the Point.

Open DOI

Michele A Basso, Sangeeta Panicker, Ginger Tansey et al.

08 1 July 2026

DOI 10.30802/aalas-jaalas-26-077

Pyometra with Concurrent Endometrial Adenocarcinoma in Laboratory Opossums (Monodelphis domestica): A Case Series of Four Animals.

Open DOI

Darielys M Diaz, Laura M Lee, Bettina Schemera et al.

The use of laboratory opossums (Monodelphis domestica) in biomedical research has increased since the 1980s, when the first colonies were established in the United States, due to their relatively low maintenance requirements and cyclical...

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09 1 July 2026

DOI 10.30802/aalas-jaalas-26-023

Trends in Age, Weight, and Health Status among Cynomolgus Macaques (Macaca fascicularis) Imported into the United States during 2014-2023.

Open DOI

Samantha Swisher, Sarah E Bowden, Anne Carroll et al.

The domestic supply of nonhuman primates (NHPs) in the United States is not adequate to meet needs for biomedical research, and many NHP research programs rely on imported animals. Since 2020, several disruptions in supply have led impor...

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10 1 July 2026

DOI 10.30802/aalas-jaalas-26-078

Postoperative Mortality Following Extended-Release Buprenorphine, Carprofen, and Bupivacaine Administration in Male ACI Rats (Rattus norvegicus)

Open DOI

Kasey L Mitchell, Andres Mejia, Jingyun Jia et al.

Extended-release buprenorphine (Bup-XR) is commonly used to manage postoperative pain in rodents while minimizing stress related to handling. An FDA-indexed Bup-XR formulation is commercially available (Ethiqa XR; Fidelis Animal Health, ...

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