Journal of mammary gland biology and neoplasia

01 7 October 2026

DOI 10.1007/s10911-026-09618-7

circ-RHOT1 Knockdown Suppresses Malignant Phenotypes and Reduces Stemness-Associated Marker Expression in Triple-Negative Breast Cancer Cells through PRMT5

Open DOI

Shengjie Liu, Mirinisa Kaicaier, Aisaide Aikelaimu et al.

02 7 October 2026

DOI 10.1007/s10911-026-09616-9

Glucocorticoid Exposure During Puberty and Early Adulthood Inhibits Mammary Progenitor Cell Differentiation

Open DOI

Marianna B. Johnson, Briana Banks, Joscelyn N. Hoffmann et al.

03 29 July 2026

DOI 10.1007/s10911-026-09612-z

Reprogramming of Metabolic and Adipokine-related Gene Expression in 3D Mammary Epithelial Organoids by Dietary Bioactive Compounds

Open DOI

Mariona Palou, Marta Alonso-Bernáldez, Andreu Palou-March et al.

Dietary bioactive compounds can modulate mammary gland gene expression, potentially influencing milk composition and infant metabolic programming. This study investigated whether selected dietary bioactive compounds modulate leptin and a...

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04 22 July 2026

DOI 10.1007/s10911-026-09614-x

Immunomodulatory mechanisms of endoplasmic reticulum stress in the tumor immune microenvironment and prediction of treatment response in HER2-positive breast cancer

Open DOI

Vavrušáková Barbora, Krejčí Lenka, Pečinka Lukáš et al.

HER2-positive breast cancer (BC) is an aggressive subtype with poor long-term outcomes in advanced disease, largely due to resistance to HER2-targeted therapies. Within the tumor-immune microenvironment (TIME), tumor and immune cells fac...

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05 17 July 2026

DOI 10.1007/s10911-026-09615-w

Differential effects of oral contraceptives on lymph node metastasis in breast cancer: role of tumor size as an effect modifier

Open DOI

Yang Saimei, Su Qiu, Xie Baodong

Objective Lymph node metastasis (LNM) is a critical determinant of breast cancer prognosis. While oral contraceptives (OC) are associated with breast cancer risk, their relationship with LNM—particularly in understudied populations like ...

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06 9 July 2026

DOI 10.1007/s10911-026-09613-y

COX-2– and IDO-associated immunomodulatory functions of stage II carcinoma-associated fibroblasts in breast cancer

Open DOI

Ladan Langroudi, Zuhair M Hasan, Masoud Soleimani et al.

The immune response against cancer is influenced by the tumor stroma. Carcinoma-associated fibroblasts (CAFs), a significant part of the stroma, are important modulators of the tumour microenvironment (TME). The current study examined th...

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07 4 July 2026

DOI 10.1007/s10911-026-09611-0

Preserving RNA quality when freezing of human milk samples must occur before extraction: Validation of methods utilized in a multi-center cohort study

Open DOI

Haijing Sun, Margaret Rabotnick, Sofia Nicastro et al.

Background Recent multicenter studies aim to define the effects of mothers’ blood glucose levels during pregnancy on mammary gland function and breast milk composition. Gene expression measured in cells in milk can serve as a liquid biop...

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08 20 June 2026

DOI 10.1007/s10911-026-09610-1

In Vitro Model of Milking Pulses and Stretching Cycles: Assessing Mechanical Effects on Bovine Mammary Cells

Open DOI

Guy Dabby, Yael German, Liron Nomi Toledano et al.

Culture models of mammary glands can be significantly enhanced by simulating physical forces, including those experienced by the tissue during milking or nursing. In particular, in vitro biophysical studies of bovine mammary cells can pr...

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09 21 May 2026

DOI 10.1007/s10911-026-09609-8

Looking in the Rear-View Mirror: How Lineage Tracing Experiments Redefined Cell Hierarchy in the Mammary Gland

Open DOI

Alexandra Van Keymeulen

Understanding the cell hierarchy of the mammary gland has been a major focus of research for several decades. This review retraces the key advances enabled by lineage tracing approaches to study stem cells and cell hierarchy in the mamma...

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10 18 April 2026

DOI 10.1007/s10911-026-09608-9

Expression of Estrogen Receptor Alpha and Ki-67 in Synchronous Canine Mammary Tumors

Open DOI

Nina Hansen, Ingrid M. Moberg, Monica Hongrø Solbakken et al.

Mammary tumors are the most common cancer in female dogs. Many dogs develop synchronous tumors, i.e. tumors occurring simultaneously or within a short time period in the same or different mammary gland. Whether synchronous canine mammary...

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