Journal of cutaneous pathology

01 20 October 2026

DOI 10.1111/cup.70238

Mast Cell Infiltration Helps Distinguish Fibrosing Alopecia in a Pattern Distribution From Androgenetic Alopecia in Scalp Biopsy

Open DOI

Azadeh Rakhshan, Fateme Ashjaazade, Sahar Dadkhahfar et al.

Background: Mast cells are key regulators of cutaneous inflammation and are known to accumulate in response to various immunological stimuli. Although their role in several dermatological conditions has been established, their specific c...

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02 20 October 2026

DOI 10.1111/cup.70236

Novel Potential Histologic Clues to Mechanical Alopecia: A Comparative Study of Traction Alopecia, Trichotillomania, and Approximately Age/Gender Matched Controls

Open DOI

Zoe Ting, Lillian Spear, Joshua Smith et al.

Mechanical stress on the pilosebaceous unit can contribute to mechanical alopecia (MA) as seen with traction alopecia (TA) and trichotillomania (TTM). While some histological features that point to TA and TTM have been described, these m...

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03 19 October 2026

DOI 10.1111/cup.70240

IgA Pemphigus in a Patient With Systemic Lupus Erythematosus ( SLE ): A Novel Association, With Combined Epidermal Intercellular IgA and Nuclear IgG Deposition on Skin Direct Immunofluorescence

Open DOI

Kelley Sharp, Tessora Chang, Jun Lu et al.

We describe the novel occurrence of IgA pemphigus in a patient with long‐standing systemic lupus erythematosus (SLE). SLE can be associated with the development of other autoimmune conditions, including cutaneous immunobullous disorders....

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04 19 October 2026

DOI 10.1111/cup.70242

A Case of Alopecia Secondary to Dupilumab in a Patient With Atopic Dermatitis

Open DOI

Jacob Myhre, Jayson Miedema, Rami N. Al‐Rohil

Dupilumab inhibits the signaling pathway of interleukins 4 and 13, and can be effective in the management of treatment‐refractory atopic dermatitis, with alopecia areata being uncommonly reported as a side effect and only limited to seve...

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05 18 October 2026

DOI 10.1111/cup.70239

PRAME Immunohistochemistry and Molecular Profiling in Undifferentiated Cutaneous Pleomorphic Neoplasms: A Case Series of 8 Tumors

Open DOI

Dylan J. Parker, Meghana Agni, Jeffrey M. Cloutier et al.

Background: Undifferentiated cutaneous pleomorphic neoplasms are diagnostically challenging, as histopathology and immunohistochemistry often fail to identify undifferentiated melanoma in lesions that instead remain classified provisiona...

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06 15 October 2026

DOI 10.1111/cup.70228

Lichen Sclerosus‐Like Changes in Acrochordons: A Case Series

Open DOI

Tamar Gomolin, Alison T. Varano, Andrew Desrosiers et al.

Lichen sclerosus (LS) is a chronic inflammatory skin disease typically affecting anogenital regions, with occasional extragenital involvement; however, its occurrence in acrochordons is seldom reported. We present eight cases of LS‐like ...

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07 15 October 2026

DOI 10.1111/cup.70235

Proof‐of‐Concept Evaluation of T‐Cell Receptor Beta Constant Region 1 and 2 Transcript in Situ Hybridization for Clonality Assessment in Mycosis Fungoides

Open DOI

Vrinda Madan, Jonathan Lai, Sima Rozati et al.

Background: Mycosis fungoides (MF) may be difficult to distinguish from inflammatory dermatoses. T‐cell receptor (TCR) gene rearrangement assays provide ancillary evidence of clonality but lack spatial resolution. We evaluated the feasib...

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08 11 October 2026

DOI 10.1111/cup.70232

GVHD ‐Associated Angiomatosis: An Overlooked Vascular Sequela of Chronic Graft‐Versus‐Host Disease

Open DOI

William E. Mbongo, Michael R. Stephens, Ruth Foreman et al.

Graft‐versus‐host disease‐associated angiomatosis (GVHD‐AA) is a rare clinicopathologic variant of chronic GVHD characterized by benign vascular proliferations arising within areas of sclerodermatous skin change. The entity was formally ...

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09 11 October 2026

DOI 10.1111/cup.70227

Granuloma Annulare‐Like Lesions in a Patient With Sarcoidosis: Case Report and Review of Literature

Open DOI

Maira A. Bhatty, Noreen Mohsin, Maximillian A. Weigelt et al.

Sarcoidosis and granuloma annulare (GA) are two granulomatous skin conditions with significant clinical and histopathologic overlap, whose diagnosis may be further complicated by their potential to co‐exist within a similar patient. Evol...

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10 11 October 2026

DOI 10.1111/cup.70234

Unmasking Iododerma: A Distinctive Histopathologic Pattern of Neutrophil‐Rich Dermatosis With Haloed Cryptococcoid Bodies in the Setting of Hydralazine Exposure and Autoimmune Serologic Abnormalities

Open DOI

Volha Lenskaya, Ana M. Ciurea, Mika Tabata et al.

Cutaneous iododerma is a rare adverse reaction to iodine‐containing compounds that may clinically and histopathologically mimic infection, vasculitis, malignancy, and other neutrophilic dermatoses. Although most commonly associated with ...

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