Journal of clinical microbiology

01 14 October 2026

DOI 10.1128/jcm.01857-25

The Brief Case: Uncommon pathogen, unusual presentation— Ureaplasma urealyticum in a post-laminectomy infection

Open DOI

Ana Collazos Blanco, Juana Alicia Fernández Gonzalez, Tatiana Mata Forte et al.

02 14 October 2026

DOI 10.1128/jcm.00296-26

Changes in observed bloodstream infection epidemiology during a single-set blood culture restriction: an interrupted time series analysis

Open DOI

Joseph B. Ladines-Lim, Bailey Van, Leigh Cressman et al.

During the 2024 US national blood culture bottle shortage, many hospitals implemented restrictions limiting blood culture collection to conserve supplies. The impact of these constraints on the microbiologic epidemiology of bloodstream i...

Read abstract

03 14 October 2026

DOI 10.1128/jcm.00409-26

Urine-based detection of Leishmania donovani antibodies using recombinant aurora kinase and otubain cysteine peptidase for noninvasive diagnosis of visceral leishmaniasis

Open DOI

Anirban Bhattacharyya, Mohd Kamran, Rudra Chhajer et al.

Visceral leishmaniasis (VL) is a fatal neglected tropical disease that requires early and accurate diagnosis to reduce mortality and interrupt transmission. Although parasitological confirmation using splenic aspirates is the gold standa...

Read abstract

04 14 October 2026

DOI 10.1128/jcm.00730-26

Challenges in establishing epidemiological cut-off values for the Burkholderia cepacia complex

Open DOI

Holly K. Huse, Carmila Manuel, Tracy McLemore et al.

The Burkholderia cepacia complex (BCC) is comprised of 24 species of gram-negative bacteria that cause opportunistic infections. While antimicrobial susceptibility testing (AST) has historically been used to guide treatment for BCC infec...

Read abstract

05 14 October 2026

DOI 10.1128/jcm.00703-26

Performance of large-volume plasma PCR for the diagnosis of invasive aspergillosis: a multicenter retrospective cohort study

Open DOI

Hanne Lamberink, Ga-Lai M. Chong, Sammy Huygens et al.

Timely diagnosis of invasive aspergillosis (IA) is hindered by moderate sensitivity of conventional diagnostic methods. Increasing plasma input volumes has been shown to improve sensitivity of plasma polymerase chain reaction (PCR), and ...

Read abstract

06 14 October 2026

DOI 10.1128/jcm.00965-26

Antimicrobial resistance in Neisseria gonorrhoeae among men who have sex with men: a 10-year analysis with implications for doxycycline post-exposure prophylaxis

Open DOI

Phyu Mon Latt, Ei T. Aung, Nyi Nyi Soe et al.

The implementation of HIV pre-exposure prophylaxis and doxycycline post-exposure prophylaxis may influence antimicrobial resistance in Neisseria gonorrhoeae among men who have sex with men (MSM). We examined trends in antimicrobial resis...

Read abstract

07 14 October 2026

DOI 10.1128/jcm.00770-26

Reducing inappropriate infectious disease serology tests through the use of decision support in a provincial electronic health system

Open DOI

R. Benson Weyant, Nathan J. Zelyas, Carmen L. Charlton et al.

Diagnostic stewardship improves patient care and reduces health costs by promoting appropriate test use. Ordering serologic tests for infectious diseases can be challenging, with indications differing based on the clinical picture, previ...

Read abstract

08 14 October 2026

DOI 10.1128/jcm.00666-26

Comparative study of a reference PCR assay targeting kinetoplast DNA and a commercial kit targeting ribosomal DNA for the molecular diagnosis of visceral leishmaniasis

Open DOI

Quentin Andreotti, Eva Lemont, Nada Kuk et al.

Visceral leishmaniasis (VL) is a severe parasitic disease that requires accurate and timely diagnosis to prevent fatal outcomes. Molecular methods, particularly quantitative PCR (qPCR), have become central to VL diagnosis because of thei...

Read abstract

09 14 October 2026

DOI 10.1128/jcm.00662-26

Dual-modal LAMP platform integrating biosensor and real-time fluorescence for rapid differentiation of Mycobacterium tuberculosis complex from nontuberculous mycobacteria

Open DOI

Junfei Huang, Xiaoyu Wei, Yonghu Wan et al.

Mycobacterium tuberculosis complex (MTBC), the primary causative agent of pulmonary tuberculosis (PTB), shares pathological features with nontuberculous mycobacteria (NTM). Some NTM species act as opportunistic pathogens that can cause N...

Read abstract

10 14 October 2026

DOI 10.1128/jcm.00232-26

Optimization of culture read times using full microbiology laboratory automation

Open DOI

Janiece S. Glover, Bailey B. Demarest, Pam J. Foster et al.

Clinical microbiology laboratories are increasingly adopting automation to meet testing demands, improve throughput, and accelerate diagnostic turnaround. This study evaluated optimal culture read times using Copan WaspLab microbiology l...

Read abstract