Impact Factor
4.78
Journal Citation Impact
Estimated influence, citation density, publishing volume, and citation integrity from the analytics table.
Citation rate
8.24
8,330 total citations
h5-index
90
h5 depth signal
Cited share
96.2%
1,032 of 1,073
Total citations
8,330
Citation footprint
Metric signal
8.39
External metric anchor
Self-citation
0.9%
71 self-citations
Citations Trend
Monthly Publications Cadence
Citing Geographic Demographics
United States
3,737
China
511
United Kingdom
385
Germany
381
Canada
280
Citing Fields of Research
Immunology
1,808
Diabetes
427
Cell Biology
350
Musculoskeletal Disorders
342
Cell Differentiation & Development
297
Publishing Activity & Reach
Volume, recency, access pattern, and citing-community signals from the journal analytics record.
All-time article footprint
5,465
Articles tracked across the journal lifetime
Indexed publication set
1,073
1,032 cited publications
Last 12 months
619
51.6 publications/month
Open access share
100.0%
619 OA publications in the last year
Leading citing country
United States
3,737 citing publications
Leading citing field
Immunology
1,808 citing publications
Latest tracked publication
13 October 2026
10 recent records available
Coverage & Indexing History
v2n1, Jan. 2017-
v1n1, 2016-
Active Coverage
Research Focus & Classification
Indexed Subjects
Immunology
Issuing & Sponsoring Bodies
issuing body
American Society for Clinical Investigation
Broad Categories
Medicine
Immunology
Musculoskeletal Disorders
Cancer & Development
Hematology
Virology
Cancer, Autophagy & Apoptosis
Diabetes
MeSH Descriptors
Biomedical Research
Latest Publications
Recent article records with DOI-first linking and condensed abstracts.
01
DOI 10.1172/jci.insight.203698
Open DOI
Detection of serotonin and serotonin-related genes reveals unique roles in human intestinal epithelial development
Although 95% of serotonin in the human body is produced in the gastrointestinal tract, most prior research work has focused on the brain. Despite its abundance in the gut, serotonin’s role in early intestinal development remains poorly u...
02
DOI 10.1172/jci.insight.198262
Open DOI
EphA2 mediates zymosan-induced inflammatory response in human monocytes independent of dectin-1
03
DOI 10.1172/jci.insight.196296
Open DOI
Locoregionally delivered PD-1 blockade augments B7-H3 targeting CAR T cell efficacy in models of glioblastoma
Glioblastoma (GBM) is a lethal brain tumor with a 95% five-year mortality rate, and remains a major unmet clinical need. An innovative approach to target GBM is administration of chimeric antigen receptor (CAR) T cells. In this study we ...
04
DOI 10.1172/jci.insight.208861
Open DOI
Plasma testosterone heterogeneity reveals genetic and demographic determinants of donor health and red blood cell quality
Testosterone is a key determinant of red blood cell (RBC) biology and susceptibility to hemolysis; however, its contribution to donor-dependent variation in RBC quality and transfusion effectiveness remains unclear. Using data from 2,357...
05
DOI 10.1172/jci.insight.206042
Open DOI
Human filarial infection reshapes CD8+ T-cell transcription and function at homeostasis and following viral activation
The role of CD8 + T cells in filarial infections remains poorly understood. Given the chronic nature of these infections, individuals living in endemic regions are frequently exposed to other pathogens including viruses. Because CD8 cell...
06
DOI 10.1172/jci.insight.207210
Open DOI
Targeting HSPA1A with geranylgeranylacetone alleviates ADTKD-UMOD via suppression of endoplasmic reticulum stress and ferroptosis
Missense mutations in the UMOD gene are a well-established genetic cause of autosomal dominant tubulointerstitial kidney disease (ADTKD). Here, we report two ADTKD pedigrees carrying de novo UMOD mutations, p.His36Tyr (H36Y) and p.Trp31C...
07
DOI 10.1172/jci.insight.210525
Open DOI
Anti-CRF antibody-mediated HPA axis modulation induces selective fat mass loss with lean mass preservation
The hypothalamic-pituitary-adrenal (HPA) axis integrates central neural processing and responses to stress with endocrine and metabolic responses. We utilized a monoclonal antibody binding corticotrophin-releasing factor (anti-CRF) to ac...
08
DOI 10.1172/jci.insight.200540
Open DOI
Keratinocyte VISTA attenuates UV light-induced skin injury by suppressing cutaneous type I interferon (IFN-I) response
Persistent production of type I interferons (IFN-Is) is a hallmark of cutaneous lupus erythematosus (CLE). Ultraviolet (UV) light stimulates IFN-I response in the skin and exacerbates CLE. Here, we identify V-type immunoglobulin domain-c...
09
DOI 10.1172/jci.insight.204059
Open DOI
Impaired regulation of nuclear calcium signals is a driver of chronic liver disease
Chronic liver disease affects over a billion people worldwide. Despite diverse etiologies, a unifying feature of chronic liver disease is the liver’s impaired ability to regenerate during progression to cirrhosis, but no common molecular...
10
DOI 10.1172/jci.insight.206342
Open DOI
Development of insulin resistance in women over the menopause transition
BACKGROUND. Body weight and insulin resistance in women increase in midlife. It is not known whether this is driven by the menopause transition or solely by chronological aging. We aimed to determine the role of the menopause transition ...