International journal of molecular sciences

01 20 October 2026

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Salivary Melatonin Levels in Comparison with Disease Features and Antihistamine Use: Prospective Follow-Up of Atopic Dermatitis Patients

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Renata Tomašević, Milena Hanžek, Tamara Sušić et al.

Background: Atopic dermatitis (AD) is a common inflammatory dermatosis often accompanied by itching and sleep disturbances. Various treatment options exist, including antihistamines (AHs), even though current clinical recommendations do ...

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02 20 October 2026

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Unveiling Telocyte Networks in the Human Superficial Fascia: A New Component of the Hypodermal Interstitial Microenvironment

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Mirko Manetti, Lucia Petrelli, Alessia Tani et al.

The human superficial fascia (SF) is a dynamic layer within the hypodermis, increasingly recognized for its role in tissue repair, lymphatic drainage, and fascial dysfunctions. Yet the complete cellular landscape of SF remains largely un...

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03 20 October 2026

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Multimodal Evaluation of [225Ac]Ac-PSMA-617 Therapy in mCRPC: PET Based Total Tumor Volume, PSA Kinetics, and Blood Biomarkers

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Ali Ebrahimifard, Shamim Bagheri, Qi Wang et al.

This retrospective analysis interrogates the value of a multimodal biomarker paradigm to characterize molecular and clinical responses to [225Ac]Ac-PSMA-617-targeted α-therapy (TAT) in cohorts of heavily pretreated metastatic castration-...

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04 20 October 2026

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Genome-Wide Identification and Analysis of the Perennial Ryegrass (Lolium perenne L.) WRKY Family Associated with Heat Stress

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Wei Chen, Nan Song, Jing Zhang et al.

Perennial ryegrass, the most widely cultivated forage and turfgrass, exhibits a relatively poor temperature tolerance, which restricts its distribution and utilization in warmer regions. WRKY transcription factors regulate diverse biolog...

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05 20 October 2026

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Beyond Classical Reward Circuits: Dorsal Striatum Proteomic Alterations in an Adolescent Phencyclidine-Induced Mouse Model of Schizophrenia and Nicotine Use

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Thainá Pereira Souza, Andrés Rodríguez-Vega, Ana Carolina Dutra-Tavares et al.

Schizophrenia and nicotine misuse comorbidity frequently emerges during adolescence. Although the dorsal striatum has received less attention than mesolimbic regions in this context, growing evidence supports its involvement in both schi...

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06 20 October 2026

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Effects of Zinc Deficiency and Supplementation on Hippocampal ZnT3, NOGO-A, IL-6, and SESN2 Expression and Oxidative Stress Markers in a Cuprizone-Induced Toxic Demyelination Model

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Adem Atacak, Elif Gulbahce-Mutlu, Gozde Acar et al.

This study investigated the effects of zinc deficiency and supplementation on oxidative stress markers and the expression of ZnT3, NOGO-A, IL-6, and SESN2 in hippocampal tissue within a cuprizone (CPZ)-induced toxic demyelination model. ...

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07 20 October 2026

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Procaine at Low Concentration Modulates Mitochondrial Features in Cultured Fibroblasts and Myoblasts: A Clue to the Cellular Mechanisms Underlying Neural Therapy

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Chiara Rita Inguscio, Giada Remoli, Ilaria Scambi et al.

Procaine is a local anesthetic used at low concentrations in a complementary medical approach, neural therapy, due to its ability to promote antioxidant and anti-inflammatory response. Previous biochemical studies showed that low concent...

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08 20 October 2026

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Plant-Derived Functional Molecules for Photoelectrochemical Water Splitting: From Molecular Design to Hybrid Materials Engineering

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Sangmin Kim, Inseo Hwang, Gihoon Kim et al.

Plant-derived molecules offer tunable coordination and surface chemistry for photoelectrochemical (PEC) water splitting. A Scopus survey retrieved 45 documents linking both topics in 2005–2025, equivalent to 0.34% of the PEC literature. ...

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09 20 October 2026

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Model-Dependent EV Biomarker Signatures: From Culture Systems to Translational Perspectives

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Giulia di Fazio, Giuseppina Poppa, Sandra D’Ascenzo et al.

Extracellular Vesicles (EVs) have emerged as key mediators of intercellular communication and, more recently, as promising biomarkers for disease diagnosis, prognosis, and therapeutic monitoring. In vitro cellular models are essential to...

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10 20 October 2026

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Comparative Chloroplast and Mitochondrial Genomics of Sorbus L. Sensu Lato: Genome Diversity, Structural Variation, and Phylogeny

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Yuxia Wu, Wenhua Yang, Yongqi Zheng et al.

Sorbus L. sensu lato represents a taxonomically complex group within Rosaceae, but organelle genome variation remains insufficiently characterized, particularly at the intraspecific level. Here, we assembled the complete mitochondrial ge...

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