Internal medicine

01 15 October 2026

DOI 10.2169/internalmedicine.e001-26

Erratum for Diffusion-weighted Whole-body Imaging with Background Body Signal Suppression Enables Simultaneous Whole-body Assessments of IgG4-related Diseases

Open DOI

Wataru Ujita, Terumi Kamisawa, Kazuro Chiba et al.

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02 15 October 2026

DOI 10.2169/internalmedicine.6981-25

Nintedanib-induced Glomerular Microangiopathy after Long-term Nintedanib Administration Presenting with Nephrotic Syndrome

Open DOI

Mizuki Watada, Yurina Yataka, Motoki Hoshino et al.

We herein report a rare case of nintedanib-induced glomerular microangiopathy (GMA) in a 77-year-old woman with idiopathic pulmonary fibrosis. The patient developed nephrotic-range proteinuria (5.9 g/gCr) after 29 months of nintedanib th...

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03 15 October 2026

DOI 10.2169/internalmedicine.6661-25

Eosinophilic Gastroenteritis during Tocilizumab Treatment for Castleman Disease

Open DOI

Hiromitsu Kaneko, Kenta Hayashino, Hiroki Kobayashi et al.

Eosinophilic gastroenteritis (EGE) is a rare inflammatory disorder characterized by eosinophilic infiltration of the gastrointestinal tract and its associated symptoms. We report a case of EGE in a patient with idiopathic multicentric Ca...

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04 15 August 2026

DOI 10.2169/internalmedicine.6315-25

Successful Non-surgical Treatment for a Duodenal Perforation Caused by the Rupture of an Intraductal Papillary Mucinous Neoplasm of the Pancreas

Open DOI

Akira Miyazaki, Hiroaki Koike, Keiichi Ito et al.

An intraductal papillary mucinous neoplasm (IPMN) was incidentally detected in a 91-year-old woman 12 years before her current admission. The patient declined additional examinations and surgical intervention. Over the subsequent years, ...

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05 1 August 2026

DOI 10.2169/internalmedicine.5836-25

Scleroderma Renal Crisis and Posterior Reversible Encephalopathy Syndrome Triggered by Non-steroidal Anti-inflammatory Drugs

Open DOI

Takaya Suzuki, Mai Ishikawa, Takuya Yamaguchi et al.

Scleroderma renal crisis (SRC) and posterior reversible encephalopathy syndrome (PRES) are rare but severe complications of systemic sclerosis (SSc). We report the case of a 44-year-old patient with SSc who developed SRC and PRES, potent...

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06 1 July 2026

DOI 10.2169/internalmedicine.6344-25

Sporadic Late-onset Nemaline Myopathy Associated with Multiple Myeloma

Open DOI

Yoshihiro Furukawa, Keiichi Hokkoku, Yuichi Furukawa et al.

Sporadic late-onset nemaline myopathy (SLONM) is a rare, acquired myopathy that is frequently associated with monoclonal gammopathy, most commonly monoclonal gammopathy of undetermined significance (MGUS). However, its association with o...

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07 1 July 2026

DOI 10.2169/internalmedicine.6236-25

Generalized Myasthenia Gravis with Anti-acetylcholine Receptor Antibodies during the Clinical Course of Spinal and Bulbar Muscular Atrophy

Open DOI

Tomoki Kawasaki, Koji Tsuzaki, Naoko Uehara et al.

A 44-year-old man with spinal and bulbar muscular atrophy (SBMA) and an anterior mediastinal tumor presented with ptosis and diplopia with diurnal variation. Dysarthria, dysphagia, and limb weakness deteriorated acutely, and developed re...

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08 1 July 2026

DOI 10.2169/internalmedicine.6258-25

A Hybrid Peripheral Nerve Sheath Tumor (Granular Cell Tumor+Schwannoma) of Cystic Duct Origin, Presenting with Gallbladder Enlargement and Abdominal Pain

Open DOI

Akira Imoto, Masahiro Yamamura, Atsushi Okuda et al.

Granular cell tumors and schwannomas rarely occur in cystic ducts. We herein report a case of a hybrid tumor consisting of a cystic duct-originating granular cell tumor and schwannoma. A 48-year-old woman was referred to our hospital wit...

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09 1 July 2026

DOI 10.2169/internalmedicine.5151-24

Differences in Coronary Microvascular Spasms Induced by Acetylcholine and Ergonovine

Open DOI

Shozo Sueda, Hiroki Ono, Hikaru Okabe et al.

Background There are no comparative studies on provoked coronary microvascular spasm (CMS) in patients undergoing both acetylcholine (ACh) and ergonovine (EM) vasoreactivity testing. Objectives We investigated the incidence of provoked C...

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10 1 July 2026

DOI 10.2169/internalmedicine.5426-25

A Rare Case of Amyloid Goiter Suspected to Be Malignant on Imaging Findings

Open DOI

Masahiro Ichikawa, Nami Suzuki, Natsuko Watanabe et al.

A 67-year-old man was diagnosed with Hashimoto's thyroiditis, and replacement therapy with levothyroxine was initiated. Ten years later, although the patient was euthyroid, ultrasonography showed an increase in goiter size and a signific...

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