Immunologic research

01 17 October 2026

DOI 10.1007/s12026-026-09856-1

Comment on “The cost-benefit of newborn screening for X-linked agammaglobulinemia and related B-cell lymphopenia”

Open DOI

Ercan Yılmaz, Erdem Topal

02 15 October 2026

DOI 10.1007/s12026-026-09860-5

Association of immune checkpoint–related polymorphisms in PD-1, PD-L1, and CTLA-4 genes with susceptibility to genitourinary cancer: a meta-analysis

Open DOI

Chih-Heng Chen, Su-Wei Hu, Chia-Chang Wu et al.

03 9 October 2026

DOI 10.1007/s12026-026-09859-y

Upregulation of cellular exhaustion-related genes and CD4 + T cell disturbances in immunological non-responders on antiretroviral therapy

Open DOI

Henrique Fernando Lopes-Araujo, Wlisses Henrique Veloso Carvalho-Silva, José Leandro Andrade-Santos et al.

Antiretroviral therapy suppresses HIV replication, but 10–40% of people living with HIV do not reconstitute CD4 + T cell counts despite viral suppression. Cellular exhaustion and alteration in the frequency of CD4 + T cell subsets are me...

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04 9 October 2026

DOI 10.1007/s12026-026-09857-0

Eupatorin interferes with NLRP3 inflammasome activation via modulation of NF-κB signaling pathway in LPS induced macrophages

Open DOI

Farheen Mansoor, Almas Jabeen, Atiya Habib et al.

05 8 October 2026

DOI 10.1007/s12026-026-09855-2

Human endogenous retroviruses antibody signatures in severe asthma phenotypes

Open DOI

Milena Fais, Rachele Campus, Elena Rita Simula et al.

Human endogenous retroviruses (HERVs) represent approximately 8% of the human genome and have been increasingly implicated in the pathophysiology of immune-related disorders. In this study, we investigated the humoral response against sp...

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06 7 October 2026

DOI 10.1007/s12026-026-09858-z

Long-term immunological impairment after early thymectomy in congenital heart disease

Open DOI

José Roberto Mendes Pegler, Débora Linhares Rodrigues, Renata de Almeida Bordim et al.

Early thymectomy during congenital heart disease repair may impair thymic output, but long-term effects across age groups remain incompletely defined. We evaluated T-cell receptor excision circles (TRECs) and a comprehensive panel of lym...

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07 6 October 2026

DOI 10.1007/s12026-026-09852-5

One threshold does not fit all: assay-specific validation of anti-tTG IgA tests for biopsy-free diagnosis of pediatric celiac disease

Open DOI

Maria Barrale, Maria Fregapane, Vincenzo Cantisano et al.

08 5 October 2026

DOI 10.1007/s12026-026-09851-6

Augmenting antitumor immunity in colon cancer via GSDMD-mediated pyroptosis induced by an attenuated Salmonella delivery system

Open DOI

Bingran Han, Xu Si, Chuanjie Liu et al.

As a major gastrointestinal malignancy, colon cancer (CC) demands more effective therapies. Gene therapy is an emerging promising strategy, and pyroptosis, a novel lytic cell death form, serves as a vital antitumor target, with Gasdermin...

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09 2 October 2026

DOI 10.1007/s12026-026-09854-3

Vitamin D status and supplementation as potential modifiers of allergen immunotherapy outcomes in respiratory allergy: A structured narrative review

Open DOI

Selda Ali, Denisa-Mihaela Iordan, Andreea-Iulia Vlădulescu-Trandafir et al.

Allergen immunotherapy (AIT) represents a cornerstone in managing IgE-mediated allergic diseases, such as allergic rhinitis and asthma. By administering controlled doses of allergens over time, AIT aims to readjust immune tolerance, ther...

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10 1 October 2026

DOI 10.1007/s12026-026-09853-4

Identification of genetic variants associated with monogenic autoinflammatory diseases in patients with Still’s disease using next-generation sequencing

Open DOI

Erdem Bektas, Pelin Ercoskun, Aynur Islamova et al.