Hippocampus

01 19 October 2026

DOI 10.1002/hipo.70141

The Strength of Target Representations Drives Mnemonic Discrimination: Evidence From Extended Delay and Hippocampal Damage

Open DOI

C. Brock Kirwan, Samuel P. Chipman, Martina K. Hollearn et al.

Mnemonic discrimination is critical for episodic memory and is dependent on the computational process of pattern separation, which allows the memory system to disambiguate prior memories from potentially overlapping new memories and avoi...

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02 14 October 2026

DOI 10.1002/hipo.70142

Chronic Electroconvulsive Shock Disrupts Hippocampal Physiology and Impairs Associative Memory in Mice

Open DOI

T. R. Zhang, N. P. Vyleta, I. Schwein et al.

Electroconvulsive therapy ( ECT ) is a highly effective treatment for depression but it has undesirable side effects on various aspects of cognition, including memory. Patients may display retrograde amnesia for autobiographical events a...

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03 14 October 2026

DOI 10.1002/hipo.70140

Homeostatic Control of Hebbian Plasticity Exerted by Action Potential‐Mediated Metaplasticity

Open DOI

Giuseppe Busetto, Bruce G. Mockett, Alessandro Marcon et al.

Hebbian plasticity, in particular long‐term potentiation (LTP) of excitatory synapses, is a positive feed‐back mechanism and has the potential to saturate its effects with negative consequences at both the single neuron and the circuit l...

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04 14 October 2026

DOI 10.1002/hipo.70138

Mapping Projectome Heterogeneity of Subiculum Neuron Cell Types

Open DOI

Ann W. Saustad, Michael S. Bienkowski

The subiculum (SUB) is the main output structure of the hippocampus, influencing diverse behaviors through its widespread cortical and subcortical connections. Our previous work creating the mouse Hippocampus Gene Expression Atlas (HGEA)...

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05 1 October 2026

DOI 10.1002/hipo.70137

Temporal Interference Modulates Medial Temporal and Frontoparietal Activity During Mnemonic Discrimination: A High‐Resolution Whole‐Brain fMRI Investigation

Open DOI

Min Sung Seo, Rebecca L. Wagner, Jordan D. Chamberlain et al.

Mnemonic discrimination—the ability to distinguish between existing memories and similar new inputs—supports accurate memory in the face of interference (e.g., in a card game, recognizing that the card you are currently seeing, the King ...

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06 1 October 2026

DOI 10.1002/hipo.70134

Adolescent Ethanol Exposure Disrupts the Mature Phenotype of Surviving Neuroprogenitors in Female Mice

Open DOI

Kaitlyn Campbell, Madison McDowell, Eymani Alston et al.

Rodent models of human adolescent binge drinking persistently reduce adult neurogenesis and induce innate immune signaling cascades, suggesting long‐lasting dysfunction in the hippocampal neurogenic niche. Nevertheless, many neuroprogeni...

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07 28 September 2026

DOI 10.1002/hipo.70136

Mental Scene and Memory Construction and the Hippocampus

Open DOI

Edmund T. Rolls

A neurocomputational theory of scene and memory construction during memory recall, prospective thinking, and autobiographical memory is described. The theory describes the nature of the representation of scenes using spatial view cells i...

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08 28 September 2026

DOI 10.1002/hipo.70108

Issue Information ‐ Editorial Board

Open DOI

09 21 September 2026

DOI 10.1002/hipo.70132

Prenatal Stress Induced by Maternal Immune Activation Disrupts GABAergic Inhibition and Mossy Fiber Plasticity in the Rat Dentate Gyrus‐CA3 Circuit

Open DOI

Johaly Anguiano‐Buenfil, Isabel Sollozo‐Dupont, Luis A. Márquez et al.

Viral infections during critical periods of pregnancy trigger inflammatory responses that alter offspring brain development and behavior, resulting in psychiatric disorder‐associated phenotypes. This condition is commonly referred to as ...

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10 20 September 2026

DOI 10.1002/hipo.70135

Impaired Synaptic Plasticity in a Rodent Model of Intimate Partner Violence‐Related Brain Injury

Open DOI

Justin Brand, Eric Eyolfson, Kirsten R. B. Suesser et al.

Intimate partner violence‐related brain injury (IPV‐BI) predominantly affects women and often reflects both structural trauma from mild traumatic brain injury (mTBI), as well as ischemia/hypoxia from non‐fatal strangulation (NFS). This p...

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