Impact Factor
3.80
Journal Citation Impact
Estimated influence, citation density, publishing volume, and citation integrity from the analytics table.
Citation rate
3.45
2,033 total citations
h5-index
46
h5 depth signal
Cited share
76.5%
458 of 599
Total citations
2,033
Citation footprint
Metric signal
3.43
External metric anchor
Self-citation
2.6%
52 self-citations
Citations Trend
Monthly Publications Cadence
Citing Geographic Demographics
United States
671
Germany
581
Italy
433
China
423
India
264
Citing Fields of Research
Synthesis
759
Drug Delivery Systems
553
Cancer Drugs
417
Protein Structure & Folding
343
Cancer, Autophagy & Apoptosis
277
Publishing Activity & Reach
Volume, recency, access pattern, and citing-community signals from the journal analytics record.
All-time article footprint
6,271
Articles tracked across the journal lifetime
Indexed publication set
599
458 cited publications
Last 12 months
444
37.0 publications/month
Open access share
56.8%
252 OA publications in the last year
Leading citing country
United States
671 citing publications
Leading citing field
Synthesis
759 citing publications
Latest tracked publication
19 October 2026
10 recent records available
Coverage & Indexing History
v1n1, Jan. 2006-
v1n1, Jan. 2006-
Research Focus & Classification
Indexed Subjects
Synthesis
Drug Delivery Systems
Cancer Drugs
Cancer, Autophagy & Apoptosis
Parasitology Studies
Protein Structure & Folding
Broad Categories
Chemistry
Pharmacology
Protein Structure & Folding
Synthesis
Cancer Drugs
Immunotherapy
Parasitology Studies
Cellular Membrane Transporters & Receptors
Cancer, Autophagy & Apoptosis
MeSH Descriptors
Chemistry, Pharmaceutical
Latest Publications
Recent article records with DOI-first linking and condensed abstracts.
01
DOI 10.1002/cmdc.70541
Open DOI
Design, Synthesis, and Biological Evaluation of Quinolin‐2‐One–Indole Schiff Base Hybrids as Potential EGFR‐Targeted Anticancer Agents Against Breast and Ovarian Cancer
A series of new quinolin‐2‐one–indole Schiff base hybrids was designed, synthesized, and tested as potential anticancer agents targeting the epidermal growth factor receptor. The designed compounds were synthesized via a multistep synthe...
02
DOI 10.1002/cmdc.70547
Open DOI
Therapeutic and Biomedical Applications of Dopamine‐Derived Scaffolds: A Comprehensive Review
Dopamine, a pivotal catecholamine, serves as a versatile scaffold in drug design due to its unique pharmacological profile and chemical reactivity. This review integrates evidence on the therapeutic applications of dopamine‐derived compo...
03
DOI 10.1002/cmdc.70535
Open DOI
The 20 th EFMC Short Course on Medicinal Chemistry Dedicated to Atypical Approaches Focusing on Protein Targets
The 20 th EFMC Short Course on Medicinal Chemistry took place from April 19–22, 2026, in Oegstgeest, near Leiden in the Netherlands. Rather than focusing on a single topic, this anniversary edition reviewed some atypical approaches in me...
04
DOI 10.1002/cmdc.70531
Open DOI
Evaluating Machine Learning Affinity Prediction Methods on Novel Lead Optimization Data: A 15‐PGDH Case Study
Recent machine learning (ML) methods for protein–ligand affinity prediction, such as Boltz‐2 and AEV‐PLIG, have been reported to approach free energy perturbation (FEP) accuracy on well‐known benchmarks. Even short of that accuracy, ML‐b...
05
DOI 10.1002/cmdc.70528
Open DOI
Tuning the Triazolotriazine Scaffold Toward Selective A 3 Adenosine Receptor Antagonists: From Molecular Recognition to Neuroprotection
A series of 2,5,7‐trisubstituted [1,2,4]triazolo[1,5‐ a ][1,3,5]triazines (TTs) was developed to identify selective A 3 AR antagonists. Guided by previous structure–activity relationship studies, the C2‐furyl substituent was replaced wit...
06
DOI 10.1002/cmdc.70533
Open DOI
Inhibitors of PIM‐1 Signaling Pathways as Anticancer Agents: Pharmacological and Structural Viewpoints
Pim‐1, a carcinogenic threonine and serine kinase, inhibits apoptosis and advances the cell cycle. It is overexpressed in several human cancers. The proviral integration site of Moloney murine leukemia virus 1 is Pim‐1. Previous studies ...
07
DOI 10.1002/cmdc.70506
Open DOI
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
This review provides an overview of recent advances in the development of multitarget drugs (MTDs) for cardiac diseases, with a particular focus on emerging molecular scaffolds and their pharmacological properties. We discuss the fundame...
08
DOI 10.1002/cmdc.70514
Open DOI
A Molecular Rationale for Tailoring the Growth Mechanisms of Biomimetic Calcium Oxalates: Guides to Simplified Proxies of Renal Stones?
We present a combined molecular simulation and experimental study of the mechanisms of calcium oxalate monohydrate formation within a biomimetic matrix. Using a double‐diffusion approach to feed calcium and oxalate ions into an agarose g...
09
DOI 10.1002/cmdc.70521
Open DOI
Beyond Single‐Target Therapy: Dual‐Acting Cannabinoid Type‐2 Receptor Modulation in Neurological Disorders
Neurological disorders such as Alzheimer's disease, Parkinson's disease, and neuroinflammatory conditions involve complex, interconnected mechanisms, including neuroinflammation, oxidative stress, cholinergic dysfunction, and synaptic im...
10
DOI 10.1002/cmdc.70526
Open DOI
Network Pharmacology in Drug Discovery: Current Advances, Challenges, and Future Directions Toward Precision Medicine
Network pharmacology (NP) is an innovative drug discovery method that provides a comprehensive view of drug–body interactions through complex biological networks. Each drug modulates specific network nodes, and understanding these intera...
Bibliographical & Catalog Notes
Title from cover.
Latest issue consulted: Vol. 1, no. 2 (Feb. 2006).
Print issues ceased with v. 10, no. 12 (Dec. 2015).
Also issued online.
Co-owned by a group of European chemical societies.