Impact Factor
3.52
Journal Citation Impact
Estimated influence, citation density, publishing volume, and citation integrity from the analytics table.
Citation rate
3.28
663 total citations
h5-index
30
h5 depth signal
Cited share
76.8%
159 of 207
Total citations
663
Citation footprint
Metric signal
3.08
External metric anchor
Self-citation
7.4%
49 self-citations
Citations Trend
Monthly Publications Cadence
Citing Geographic Demographics
United States
543
Germany
121
China
102
India
83
United Kingdom
75
Citing Fields of Research
Separation Techniques
485
Industrial Microbiology
290
Bacteriology
156
Immunotherapy
108
Drug Delivery Systems
98
Publishing Activity & Reach
Volume, recency, access pattern, and citing-community signals from the journal analytics record.
All-time article footprint
6,171
Articles tracked across the journal lifetime
Indexed publication set
207
159 cited publications
Last 12 months
98
8.2 publications/month
Open access share
46.9%
46 OA publications in the last year
Leading citing country
United States
543 citing publications
Leading citing field
Separation Techniques
485 citing publications
Latest tracked publication
11 October 2026
10 recent records available
Coverage & Indexing History
v14n2, Mar.-Apr. 1998-
v14n2, Mar.-Apr. 1998-
Active Coverage
Research Focus & Classification
Indexed Subjects
Separation Techniques
Issuing & Sponsoring Bodies
Contributor
American Institute of Chemical Engineers
Contributor
Society for Biological Engineering
Contributor
American Institute of Chemical Engineers. Food, Pharmaceutical, and Bioengineering Division
Contributor
American Chemical Society
Broad Categories
Biotechnology
Separation Techniques
MeSH Descriptors
Biomedical Engineering
Food Technology
Technology, Pharmaceutical
Latest Publications
Recent article records with DOI-first linking and condensed abstracts.
01
DOI 10.1002/btpr.88561
Open DOI
Adaptation of suspension Vero cells to commercially available cell culture media and enhanced production of vaccine‐strain mumps virus
Vero cells (referred to as “Vero” henceforth) are a commonly used host for the production of a wide variety of vaccines, but due in part to the typically anchorage‐dependent nature of the cells, Vero cells also pose multiple challenges d...
02
DOI 10.1002/btpr.88559
Open DOI
Design and scale‐up of a mixed‐substrate fed‐batch strategy for enhanced HPV VLP production in Komagataella phaffii
Production of human papillomavirus (HPV) virus‐like particles (VLPs) in Komagataella phaffii is often constrained by methanol‐associated toxicity and suboptimal feeding strategies during induction. In this study, a microbioreactor‐based ...
03
DOI 10.1002/btpr.88560
Open DOI
Development and application of a mechanistic model for protein A resolution of a bispecific antibody for process characterization and optimization
Regeneron's bispecific technology, based on a fully human IgG antibody construct, consists of two distinct heavy chains and a common light chain co‐expressed in a single cell. The co‐expression of the two distinct heavy chains, one of wh...
04
DOI 10.1002/btpr.88556
Open DOI
BioOps : Enabling MLOps for scalable and flexible model‐centric process control in biopharmaceutical development
The deployment of advanced modeling and machine learning in biopharmaceutical process control has been limited by legacy fragmented automation infrastructure and a lack of model lifecycle governance. We present BioOps, a modular automati...
05
DOI 10.1002/btpr.88557
Open DOI
Evaluation of media intensification strategies in perfusion
Upstream continuous manufacturing of biologic therapeutics has been an attractive method to address growing demand. However, maintaining high cell densities (>100 million cells/mL) for long periods of time (>25 days) requires large amoun...
06
DOI 10.1002/btpr.88555
Open DOI
Small scale purification and biophysical characterization of haptoglobin derived from human Cohn fraction IV
Haptoglobin (Hp) is a polymorphic acute phase α ‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by ...
07
DOI 10.1002/btpr.88547
Open DOI
DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography
Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography...
08
DOI 10.1002/btpr.88558
Open DOI
Issue Information
09
DOI 10.1002/btpr.88554
Open DOI
Impact of single‐use bioreactor bag materials on Spodoptera frugiperda cell expansion for recombinant adeno‐associated virus manufacturing
Recombinant adeno‐associated virus production for gene therapy applications commonly relies on the Spodoptera frugiperda 9 (Sf9) baculovirus infection platform. The process encompasses cell expansion from flasks through intermediate‐scal...
10
DOI 10.1002/btpr.88553
Open DOI
Bone marrow‐like viscosity affects imatinib resistance in chronic myeloid leukemia
Chronic myeloid leukemia (CML), one type of blood cancer, is a clonal myeloproliferative disorder of hematopoietic stem cells that originated from bone marrow (BM). Imatinib (IM) resistance in CML treatment has been frequently reported, ...
Bibliographical & Catalog Notes
Title from cover.
Print issues ceased with v. 30, no. 6 (Dec. 2014).
Also issued online.
Vols. for 1985-1989 issued by the Food, Pharmaceutical, and Bioengineering Division of AIChE; 1990- cosponsored by the American Chemical Society and the American Institute of Chemical Engineers.
Official publication of: the American Institute of Chemical Engineers, <2010->
Vols. for 1985-1989 include FPBE news as a special section. Earlier and later issues of FPBE news are published separately.
Vol. 6, no. 1 (JAN 1990)19890828 Notice not published Printed on acid-free paper