Biology open

01 16 October 2026

DOI 10.1242/bio.062896

Genetic disruptions of Hsp90-encoding genes impacted short-term evolutionary trajectories of antifungal resistance in Saccharomyces cerevisiae

Open DOI

XueyingC.Li(李雪莹), MiaoLiang(梁淼), XinyingHan(韩欣颖) et al.

Laboratory evolution has been a powerful approach to address questions about evolvability. It has been debated whether the molecular chaperone, heat shock protein 90 (Hsp90), buffers or potentiates the effects of variation, and, conseque...

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02 15 October 2026

DOI 10.1242/bio.062716

Validation of an open-source hardware for cardio-physiological studies in fish: A statistical equivalence study with a widely used research-grade electrophysiological recording system.

Open DOI

Luca Pettinau, Pierpaolo Congia, Katja Anttila

Monitoring heart rate (fH) accurately is fundamental for fish eco-physiological studies. However, these measurements rely heavily on expensive experimental tools. Here, we aimed to validate BITalino, an inexpensive, open-hardware biosign...

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03 15 October 2026

DOI 10.1242/bio.062877

Lampricide 3-trifluoromethyl-4-nitrophenol (TFM) impacts whole-organism oxygen consumption in non-target fishes

Open DOI

Melina Göbel, Aiden Moore, Tabitha Hafenbrak et al.

The application of the lampricide TFM (3-trifluoromethyl-4-nitrophenol) to streams infested with larval sea lamprey constitutes the backbone of the Sea Lamprey Control Program in the Laurentian Great Lakes, but native species have greatl...

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04 15 October 2026

DOI 10.1242/bio.062762

A proposed GABAergic pathway in the feeding neural network is associated with learning performance in conditioned taste aversion in Lymnaea

Open DOI

Ayaka Itoh, Samui Chiba, Yoshimasa Komatsuzaki et al.

Conditioned taste aversion (CTA) provides a useful model for investigating the neural mechanisms underlying long-term memory (LTM). In Lymnaea stagnalis, CTA can be induced by pairing sucrose, which initially elicits feeding responses, w...

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05 15 October 2026

DOI 10.1242/bio.062632

Dynamin-2 promotes Atg9A retrieval from phagophores during autophagy

Open DOI

Andrew Caliri, Alejandro Martorell-Riera, Panagiota Kolitsida et al.

Autophagy involves the rapid growth of phagophores through membrane addition. This growth is triggered by vesicles containing the Atg9A protein. However, Atg9A is not incorporated into mature autophagosomes. We now demonstrate that Dynam...

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06 13 October 2026

DOI 10.1242/bio.062872

One dataset, four meta-analyses: synthesising mean effects and heterogeneity within and among populations

Open DOI

Haley Lacza, Ayumi Mizuno, Coralie Williams et al.

Ecological syntheses (meta-analyses) usually ask ‘what is the average effect?’ But many questions also depend on whether outcomes become more or less variable and whether effects are predictable across contexts. We show how one dataset c...

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07 12 October 2026

DOI 10.1242/bio.062786

Experimental evidence that dietary antioxidants induce an antiviral transcriptomic signature in a wild seabird

Open DOI

Manrico Sebastiano, Marcel Eens, Olivier Chastel et al.

Infectious disease emergence in natural systems is driven by complex host–pathogen–environment interactions. Nutritional factors, particularly dietary antioxidants, can modulate physiological states by enhancing immune function and mitig...

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08 12 October 2026

DOI 10.1242/bio.062585

Nuclear blebs are composed of variable chromatin states and display increased transcription initiation relative to elongation

Open DOI

Madeleine Clark, Antonela Losada, Sonia Jahng et al.

Nuclear blebs are herniations of the nucleus that occur in many human conditions including aging, heart disease, muscular dystrophy, and many cancers. Nuclear blebbing causes nuclear rupture and cellular dysfunction. However, understandi...

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09 12 October 2026

DOI 10.1242/bio.062609

Chlamydomonas γ-tubulin mutations reveal a critical role for γ-TuRC in maintaining the stability of centriolar microtubules

Open DOI

Yuki Nakazawa, Naoto Kubota, Mao Horii et al.

The centriolar triplet microtubule consists of an A-tubule with 13 protofilaments, and B- and C-tubules, each with 10 protofilaments. Although the formation of the triplets has been shown to require γ-tubulin, its specific role in the fo...

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10 12 October 2026

DOI 10.1242/bio.062674

Correlating relative light sensitivity to retinal visual gene expression patterns in three African cichlid fish species

Open DOI

Gerrit Potkamp, Elena Zhemchuzhnikova, Felicity van Geresteijn et al.

Visually guided behaviour requires adequate visual sensitivity. Hypotheses on the evolution of vertebrate visual systems largely rely on the assumption that the retinal expression pattern of visual genes is a major determinant of visual ...

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